This loop will start and finish in Parkersburg, WV. Leave Parkersburg on WV-14 toward Elizabeth. Continue through Elizabeth to the town of Spencer. Go left on U.S.33 for less than a mile. Take a right on U.S.119 and continue for 8/10th mile where you will go left on WV-36. Follow WV-36 for about 30 miles till you come to Interstate 79. Go north on I-79 for 6 miles exiting at WV-16. Follow the signs for WV-16 north, through Grantsville, Smithville, Harrisville, Ellenboro and ending in St.Mary's, WV. Go left on WV-2 in St. Mary's and follow back to Parkersburg.
There are some scenic valleys and hill top views along this route. It takes you through several small country towns where everyone seems to enjoy seeing visitors. The last portion of the loop takes you along the Ohio River from St.Mary's most the way to Parkersburg.
This is a great route for sport and sport touring types. Lots of curves and twisties in the first three quarters of the route. Then lots of straight two lane highway at the end. WV-14 and WV-16 offer some great twists and turns although my favorite is WV-36 from Spencer to I-79. Just plain sweet for the sport rider. Not sure this loop would be great fun on a large touring bike. Have observed many sport bikes on this route. If for some reason you choose not to complete the entire loop there are several bailout options such as WV-47 and U.S.50 which will both take you back to Parkersburg.
With all the small towns along the way there are numerous restaurants and stops along the way. When you arrive at Harrisville you can detour a short distance and enjoy North Bend State Park.